Tricuspid Regurgitation
More than heart, and beyond the numbers.
There is a growing and unmet need for patients struggling with TR, a progressive heart valve disease that diminishes quality of life and increases the risk of death.
Of people > 65 yrs have Moderate / Severe TR 1,2
Patients In the US & EU suffer from TR1,2
What is Tricuspid Regurgitation?
Tricuspid Regurgitation occurs when blood flows backwards through the tricuspid valve. This creates less blood flow to the lungs, causing the heart to work harder to pump blood, resulting in fatigue, swelling, and shortness of breath.
Normal Valve
An effective tricuspid valve fully opens and closes, pumping blood to the lungs and ensures effective heart function.
Leaky Valve
When the Tricuspid Valve doesn’t close properly, regurgitation of blood in the wrong direction occurs.
A progressive disease with a progressive solution.
A healthy valve enables normal right heart function.
When TR occurs, blood flows backwards, causing symptoms.
Symptoms can include fatigue, shortness of breath, ankle and abdominal swelling.
In advanced cases, the disease will cause heart failure and lead to further health issues.
1. D'Arcy JL, Coffey S, Loudon MA, et al. large-scale community echocardiographic screening revelas a major burden of undiagnosed valvular heart disease in older pople: the OxVALVE population cohort study. European Heart Journal 2016;37:3515-3522.
2. Topilsky Y, Maltais S, Inojosa JM, et al. Burden of tricuspid regurgitation in patients diagnosed in the community setting. JACC Cardiovascular imaging 219;12:433-442.